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The patented PFL Powderflex provides continuous and accurate dosing of small to medium quantities of powder, whether controlled loading of powders in continuous production processes or dosing of predetermined accuracy is required. This technology was originally developed for plasma and spray coatings, but is currently used in many areas. PFL extracts powder from any container and transports it over long distances. Its simple design ensures minimal maintenance, making it easy to quickly replace the product. The characteristics of the powder during transfer do not change. PFL is to powder what a peristaltic pump is to liquids. The system consists of two small calibrated chambers, each equipped with a flat filter at the top. A virtually continuous powder flow or precise volumetric dosing is ensured by a unique valve system. The combined action of vacuum and pressure alternately fills and empties the chambers at high frequency. The transmission rate can be easily adjusted by changing the chamber volume or changing the frequency.
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PAT contributes to a better understanding of the process by measuring critical quality attributes. Dec mainly uses Process Analytical Technology in conjunction with the PTS Batchmixer® for powder mixing or microdosing applications. PAT blending can be used to check in-line blending efficiency with a real-time NIR spectrometer that is installed in the circulation line. The technology is not intrusive, will not disturb the circulation of the powder and does not add cleaning problems. The end point of mixing can be determined using the standard deviation of the movable block without prior calibration. Microdosing - Built-in Powder Sensor Built-in weight measurement is an important advantage when there is a problem with scale integration or response time. Dec can provide a non-contact sensor based on microwave technology that can instantly measure weight and percent relative humidity. The sensor is installed directly at the outlet of the dosing unit. The measurement is not intrusive and gives an instant response.
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Primary Sealing OEB 3-4 Storing chemicals and API products in bags or sleeves is standard practice. In the manufacture of pharmaceutical products, sleeves must have special properties to prevent contamination of the product. Separate bags should not be used to ensure GMP compliance and internal filling of bags or sleeves as both product and operator may be exposed during bag removal and replacement. To prevent the use of a complicated protective casing, the CLS Continuous Liner System is an elegant and economical solution.